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Additionally, acteoside, a major active compound, has been reported to alleviate renal fibrosis and glycolipid metabolic disturbances by reducing oxidative stress and inflammation in -cells, modulating the unfolded protein response, improving mitochondrial dynamics, and enhancing -cell function and insulin secretion (69)

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When the peptide is reconstituted and diluted to typical nanomolar or low micromolar working concentrations for in-vitro assays, the final TFA concentration is extremely low and generally considered to have a negligible effect on most biological systems