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Methylene blue is used off-label for several medical conditions, including vasodilatory shock (also called distributive shock), a medical emergency in which the body can't distribute sufficient blood to the heart, brain, and kidneys

see discussion of transition metrics elsewhere), and it consistently tracks Phase III contracts and uses these Phase III numbers as a key metric for success (see Figure 4-5)

Third-party laboratory testing with published Certificates of Analysis (COA) showing purity levels above 98% indicates a supplier taking quality seriously