The medication is administered once weekly via subcutaneous injection, with doses typically initiated at 2.5 mg (an initiation dose not intended for glycemic control) and gradually titrated upward (5 mg, 7.5 mg, 10 mg, 12.5 mg, to a maximum of 15 mg) based on glycemic response, weight loss goals, and tolerability
Some studies have also observed that Ozempic can reduce body weight and fat mass independently of its effects on blood sugar control
Clinical Evidence: Weight Loss Outcomes and Effectiveness The SURMOUNT trials, which tested tirzepatide, showed average weight loss of 20.9% at the highest dose over 72 weeks, with some participants achieving losses exceeding 25%
If nausea does show up as you ramp back up, the usual strategies still apply, and it helps to know the typical GLP-1 side effects timeline so you know what is expected and what is not