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The mechanism difference that matters Semaglutide is a single-agonist it mimics GLP-1 (glucagon-like peptide-1)

The active compound in Mounjaro is tirzepatide, a medication originally developed to manage type 2 diabetes

While some appreciate the daily routine of a pill, others find the once-weekly injection more manageable

Current Neurophysiological and Clinical Evidence Non-invasive brain stimulation offers a potential alternative, non-pharmacologic approach to treat unipolar depression and treatment resistant depression (TRD), even though there is some evidence about the efficacy and safety of non-invasive neuromodulation techniques to treat unipolar depression, especially in the case of ECT and rTMS (92)