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HC neutrophils were cultured with SLE IgG (3.6 g L -1 ) and/or IFN- (10^5 U ml -1 ) for 4 or 16 hours and cells were stained with SYTOX Green for the detection of NETs

The research results provide information that will help managers and decision makers to develop more strategic and flexible management approaches

Where results are borderline, measurement of methylmalonic acid (MMA) or holotranscobalamin (active B12) may help clarify the picture, as recommended in NICE CKS guidance on B12 and folate deficiency anaemia