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One class of drugs that are commonly debated about for their interactions with semaglutide are antidepressants, specifically selective serotonin reuptake inhibitors (SSRIs) like Lexapro or Zoloft

Severe neurological symptoms: In cases of advanced deficiency with symptoms such as tingling, numbness, gait instability or memory problems, a rapid and high dose is necessary to prevent permanent nerve damage

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Adjustments to the treatment plan may be needed to ensure the patient can continue taking semaglutide without too much discomfort