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However, whereas PZQ is active against the adult developmental stages and against young schistosomula within a day or so of infection, it displays poor efficacy against schistosome eggs and the developing and migrating immature schistosomula and young adult forms [12]

Curcumin has been investigated in autoimmune and inflammatory disorders, with several trials demonstrating reduced cytokine levels and improved quality-of-life scores (219221)

Prior reports concluded small or no dementia risk difference between initiation of GLP1 receptor agonists versus SGLT2 inhibitors [16, 25, 26], consistent with our study