Focusing on overall health and well-being is important rather than just the number on the scale.
Bioorg Med Chem Lett 20 , 260265, (2010)
For patients who did experience side effects, clinicians controlled symptoms by reducing the dose temporarily, providing basic home advice such as eating small meals or bland foods, and monitoring for evidence of dehydration
Certainly, we do see collaboration between industry, academia and the government, and scientists doing research in other countries. Holst himself has also co-founded companies based on his research, including Antag Therapeutics, which is developing a novel therapeutic peptide for metabolic and cardiovascular autonomic diseases, and Bainan Biotec, which has a first-in-class-drug in pre-clinical development for the treatment of osteoporosis