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During mastication they are enzimatically converted into thiocyanates, goitrin metabolites, that cause a competitive inhibition of the sodium/iodide symporter, thus inhibiting the thyroid hormones synthesis and possibly causing hypothyroidism [156]

The peptide's combined effect of stimulating new collagen production while suppressing matrix metalloproteinase expression (the enzymes that break down collagen) provides a mechanistically rational approach to photoaging that operates through different pathways than retinoids or sunscreen

Human Melatonin-Metabolite Study A 2021 publication examined sublingual AEDG in women aged 40 to 50 who primarily worked night shifts