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However, the modern microdosing movement began when a psychologist, James Fadiman, in 2011, described microdosing methods and personal experiences from people in his book The Psychedelic Explorers Guide

This early detection is invaluable, allowing individuals and families to make informed decisions about their health and future

Biomarkers may be related to the disposition and metabolism of the drug (such as APAP protein adducts) or to the endogenous response of the host to the drug