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Tight junctional abnormality in multiple sclerosis white matter affects all calibres of vessel and is associated with blood-brain barrier leakage and active demyelination

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Therefore, since the early 1990s, we have presented stable gastric pentadecapeptide BPC 157, and its pleiotropic beneficial effects, acting also via the per oral route [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40], as a late advantage of Robert and Szabos concept of cytoprotection [41,42,43,44,45,46,47,48,49]