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The biological footprint of GHK-Cu in the published research includes copper-dependent extracellular matrix processes (notably through the copper-dependent enzyme lysyl oxidase, which cross-links collagen and elastin), broad effects on gene expression characterized in transcriptomic studies, antioxidant and redox-related effects connected to copper biochemistry, effects in wound-healing and tissue-repair research models, and effects in hair follicle biology research

Funding for clinical trials hard to come by Sikiri maintains that a large part of his studies were published in high-impact factor journals