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Acknowledgements This project was supported by funds from an Invest in Research Award from the Princess Margaret Cancer Foundation, a Medicine by Design (MbD) Award from the University of Toronto, a New Investigator Award from the Leukemia Research Foundation, and a Project Grant (PJT-175186) from the Canadian Institutes of Health Research

The Philippines FDA has issued a formal warning against high-dose unsupervised cosmetic IV glutathione, and a 2025 case series in the International Journal of Dermatology documented liver function abnormalities in approximately half of high-dose IV-treated participants in unmonitored settings, which is precisely why the DermaVue protocol restricts dosing to the 400 to 1200 mg clinical range and enforces hepatic monitoring

Our testers found that it required a fair amount of stirring or shaking to fully incorporate, and some sediment tended to settle at the bottom of the glass if left sitting for several minutes

Instrument control and data acquisition was achieved via LabSolutioFns software (Shimadzu Corporation, Kyoto, Japan)