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Dogs taking the supplement, which provided 225 mg of SAMe and 82 mg of silybin-phosphatidylcholine complex (24 mg of silybin) per day, throughout chemotherapy were less likely to exhibit increased biomarkers of liver damage and were less likely to have their chemotherapy treatments delayed due to increased liver enzyme activity

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Figure 2 ALC regulated hepatic mRNA and protein levels of cholesterol metabolism-related genes in mice To clarify the mechanism by which ALC affects plasma lipid levels in mice, we analyzed hepatic gene and protein expression related to cholesterol metabolism