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Through structured preconception counseling, contraceptive planning, and coordinated care, clinicians can help patients navigate therapy safely and effectively

GIP Receptor Agonism Enhances insulin secretion in response to glucose May offset nausea from GLP-1 activity Synergizes with GLP-1 for greater metabolic effects 3

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with a mean increase of 8 points) and tirzepatide (SUMMIT), appears to be greater than what has been reported for other HFpEF trials investigating the benefits of angiotensin receptorneprilysin inhibitor (Paragon-HF), sodiumglucose cotransporter 2 inhibitors (EMPEROR-Preserved, DELIVER) and spironolactone (TOPCAT)