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We also demonstrated that ectopic expression of wild-type mTOR, constitutively activate S6K1, or downregulated 4E-BP1 partially prevented rotenone-induced neuronal apoptosis, suggesting that rotenone-induced neuronal loss in PD may be prevented by activating mTOR signalling 15

Significance was determined by unpaired two-tailed Students t -test ( e , f ) and two-way ANOVA with Tukeys multiple comparison test ( h , i )

It is derived from a peptide sequence originally identified in gastric protein research and is frequently referenced in peptide chemistry, molecular biology, and biochemical research literature