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The peptide is not FDA-approved and has never undergone Phase I clinical trials to establish human toxicity thresholds, drug interactions, or long-term organ effects

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The extract of Rhizoma Pinelliae pedatisectae exhibited protective action in a dose-dependent manner and reported to enhance antioxidant enzyme, superoxide dismutase (SOD) activity and reduce malondialdehyde (lipid membrane damage marker/oxidative stress marker), and other inflammatory markers such as TNF- and IL-1

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