semaglutide with cagrilintide + Cagrilintide–semaglutide (CagriSema) as an add-on

doi:10.1093/sleep/34.2.225

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Thus, claims must be narrowly tailored to avoid the implication that they will offset the effects of GLP-1 drugs

Additional considerations include diabetic retinopathy status (semaglutide may worsen retinopathy in some patients with pre-existing disease, particularly with rapid A1c improvement), history of pancreatitis (use GLP-1 agents with caution), and upcoming surgical procedures (discuss with your surgical/anesthesia team due to effects on gastric emptying)