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Those were originally intended for use with diabetes and function by stimulating the release of insulin from the pancreas, which lowers blood sugar, as well as slowing the digestion of food in order to reduce appetite, which promotes weight loss

Although the atherosclerotic CV disease risk reduction and CKD progression benefits of SGLT-2 inhibitors may be found to be a class effect in future, the evidence for ertugliflozin (a third SGLT-2 inhibitor recently deleted from the market in Australia) is less robust with further studies ongoing

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