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Extending Phase 2 from four weeks to six or eight weeks is better than pushing to Phase 3 while still struggling with nausea at 0.5mg
The Data: In 2026, a major Cochrane systematic review of 22 randomized trials found that intermittent fasting produced only modest results (average 25% weight loss), while semaglutide users typically see 15% to 20% reduction in total body weight
This makes it harder to make sure that everyone gets the same amount
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