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21 Pharmacists should also counsel patients on the importance of maintaining adequate hydration, especially in the presence of vomiting or diarrhea, to prevent dehydration and reduce the risk of acute kidney injury

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External resources PubMed: Pharmacokinetics and clinical implications of semaglutide NCBI StatPearls: Tirzepatide pharmacology and pharmacokinetics New England Journal of Medicine: Retatrutide phase 2 trial data PMC: Clinical recommendations for managing GLP-1 GI adverse events For researchers committed to mastering their GLP-1 protocols with precision, SeekPeptides provides the most comprehensive resource available

GLP-1 is produced by specialised cells, known as L-cells, which are found predominantly in the lower part of the small intestine and the colon