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Researchers who need to replicate the foundational incretin literature, establish single-receptor baselines for comparative studies, or specifically study GLP-1R mechanisms without the additional variables introduced by dual or triple agonism will find GLP-1(Sema) is still the correct compound for those protocols

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The study found that in a pool of 16,827 patients, nonarteritic anterior ischemic optic Neuropathy (NAION) increased more than four times for people taking semaglutide compared to those who took another drug