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In Supplementary Fig

For vitamin B 12 labeling purposes, 100% of the daily value was 6.0 g, but on 27 May 2016, it was revised downward to 2.4 g (see Reference Daily Intake)

Circulation problems in fingers and toes [Peripheral vasculopathy, including Raynaud's phenomenon] Instruct patients beginning treatment with VYVANSE about the risk of peripheral vasculopathy, including Raynaud's phenomenon, and associated signs and symptoms: fingers or toes may feel numb, cool, painful, and/or may change from pale, to blue, to red