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Ipamorelin has a much shorter half-life of approximately 23 hours, requiring more frequent subcutaneous injections to sustain its growth hormone-releasing effects

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Hierarchical PI3K/Akt/Nrf2 Signaling Underlies GPR68s Anti-Ferroptosis Effects We provide compelling evidence that GPR68 activates PI3K/Akt signaling to drive Nrf2 nuclear translocation, a critical antioxidant mechanism