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Because no controlled human trials exist, especially in female populations, much of the conversation is based on speculation, anecdote, and animal data

In rats given BPC-157, serotonin levels in the brain increase in specific regions while simultaneously decreasing in other regions, such as the hippocampus.[ref] A 2020 study found that BPC-157 reduced leaky gut syndrome by stabilizing gut permeability after NSAID use.[ref] Reducing leaky gut theoretically can affect the gut-brain axis and reduce inflammation

Peptides with added preservatives or stabilizers Some compounding pharmacies add extra preservatives or stabilizers

have raised hopes for possible reclassification, although no changes have occurred yet