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Similar content being viewed by others Introduction Melanocortin 4 receptor (MC4R) is a G-protein-coupled receptor that activates adenylate cyclase

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We show that GLP-1(2836) entered mouse caSMCs and ECs by macropinocytosis and activated sAC, as evidenced by the increased production of cAMP in caSMCs from WT but not sAC / mice