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Leptin, neuroinflammation and obesity

HCPCS code J3398 (Injection, voretigene neparvovec-rzyl, 1 billion vector genomes) is for a gene therapy product indicated for a rare mutation-associated retinal dystrophy

Some individuals without a gallbladder may however experience stronger gastrointestinal side effects during treatment, including nausea, bloating, or diarrhoea, particularly while the body adjusts to dose increases

Additionally, there are concerns about the potential teratogenic effects of GLP-1 agonistsspecifically, whether these medications could affect fetal organ development or lead to adverse outcomes such as congenital malformations or low birth weight