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Wegovy's cardiovascular indication rests on a large outcomes trial described in its label, in which 8,803 patients were exposed to Wegovy for a median of 37.3 months and 8,801 to placebo for a median of 38.6 months, with a primary endpoint of time to first cardiovascular death, nonfatal myocardial infarction or nonfatal stroke

doi: 10.1093/humupd/dmp008 142 MoranLJTassoneECBoyleJBrennanLHarrisonCLHirschbergALet al

An accurate stable isotope dilution gas chromatographic-mass spectrometric approach to the diagnosis of guanidinoacetate methyltransferase deficiency

For the PAG analysis, counts were performed across 0.21 mm postrior to bregma 2.488 mm (two sections were selected, 30 m in thickness, one in every seven)