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To address this, we performed transcription profiling using Bru-seq and identified genes involved in cellular stress response, steroid metabolism, transcription and cytoskeleton organization as significantly altered by both GSTO1 siRNA and C1-27

May influence aspects of immune function through antioxidant and stress-response pathways

Research demonstrates that both aerobic exercise and resistance training can greatly increase glutathione levels

These effects could be more pronounced with concomitant use of hydrocodone bitartrate and acetaminophen tablets and both CYP3A4 and CYP2D6 inhibitors, particularly when an inhibitor is added after a stable dose of hydrocodone bitartrate and acetaminophen tablets is achieved (see WARNINGS)