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In addition to a decrease in peripheral levels of LAC, LAC levels are decreased by 4060% in the hippocampus and prefrontal cortex of rodents with depressive-like behaviors, including the Flinders Sensitive Line (FSL) rats [30]

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Jieduquyuziyin prescription enhances CD11a and CD70 DNA methylation of CD4(+) T cells via miR-29b-sp1/DNMT1 pathway in MRL/lpr mice

For example, in a randomized, double-blind, placebo-controlled trial in 60 participants diagnosed with an acute MI, neither mortality nor echocardiographic measures of cardiac function differed between patients treated with intravenous L-carnitine (6 g/day) for seven days followed by oral L-carnitine (3 g/day) for three months and those given a placebo (49)