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The unexpectedly profound weight loss observed in diabetes trials drove development of a higher-dose formulation Wegovy (up to 2.4 mg weekly) which received FDA approval in 2021 and EMA approval in 2023 specifically for chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity
Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated substantial weight loss in participants with obesity, though these findings were generated under tightly controlled conditions with rigorous medical supervision
Prior, Stella Leung, William D
This is crucial in wound healing, as improved blood flow supports tissue regeneration by delivering oxygen and nutrients to the damaged area
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