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Adipocyte Metabolism: Investigated for its ability to reduce white adipose tissue mass by shifting cellular metabolism away from storage and towards energy expenditure (without affecting food intake in murine models)
Weight regulation : In mouse studies, systemic administration produced a progressive reduction in body weight and up to a ~35% decrease in white adipose tissue mass
The 2021 Akar paper in Journal of Obstetrics and Gynaecology documented anti-proliferative activity of small-molecule NNMT inhibitors in HeLa cell systems (PMID 33645410)
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