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Such bidirectional interaction between hyperandrogenism and insulin resistance/hyperinsulinemia likely plays a key role in the pathogenesis of PCOS 12,13,14 , since elevated testosterone promotes obesity and insulin resistance/hyperinsulinemia by altering body composition and insulin signaling in skeletal muscle and adipose tissue, while hyperinsulinemia contributes to increase androgen levels via ovarian-dependent mechanisms 5

P value of less than 0.001 and 0.05 was considered to indicate statistical significance

Unfortunately, various factors such as aging, chronic diseases, and environmental stressors can lead to decreased levels of glutathione

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