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Given the serious shortcoming in available human evidence, further research with stronger designs (i.e

Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms

Intriguingly, recent research has shown that lactate is not only essential for efferocytosis but also for sustaining efferocytosis-induced macrophage proliferation, a process responsible for increasing the number of macrophages capable of performing continuous efferocytosis, thus contributing to the resolution of inflammation and tissue repair [87] (Fig