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Numerous gut- and brain-derived peptides exert potent anorectic or orexigenic effects, often with effect sizes comparable to or exceeding those of GLP-1 in preclinical models

L-carnitine modest, shrinking effect A 2016 meta-analysis of 9 RCTs (n=911) found carnitine users lost about 1.33 kg more than controls, and a larger 2020 meta-analysis of 37 RCTs (n=2,292) found roughly 1.21 kg

NS3 is a multifunctional protein, with an N-terminal serine protease domain and a C-terminal RNA helicase/NTPase domain

Its also known as betaine, a naturally occurring nutrient found in foods like beetroot, spinach, and whole grains