will you gain weight back after semaglutide Can Stop Ozempic Without Gaining Back? Does stopping GLP-1s make you

While some clinical trials have explored higher doses, 2.5 mg is generally the upper limit for safe and effective weight management under current medical guidelines

10.1371/journal.pone.0015384 PLoS One 35 CreganS

[They] have simply fluctuated between five to 10 pounds after a significant weight loss of 50 to 70 pounds. Because semaglutide is a peptide drug, and peptides are like messenger systems, Decotiis says the drug might be able to rewire appetite over time, giving people struggling with diabetes and weight loss a greater chance of improving their eating habits

Higher doses provide for more weight loss with a slightly higher rate of nausea