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It is a clinically proven treatment that helps adults with obesity lose weight while also reducing the risk of cardiovascular events in patients who also have heart disease

This has led to interest in melatonins potential protective role in neurodegenerative disorders, cardiovascular health, and cancer prevention, although conclusive evidence in humans remains limited

One of the primary limitations is the relatively small sample size, which could affect the generalizability of the findings

A reduction in total choline in long COVID is of interest in the context of the recently reported association between blood clots and brain fog, and earlier animal studies showing that choline might prevent intravascular coagulation