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At 56 weeks, mean weight loss was 9.8% at the recommended dose and 10.9% at the top dose, versus 1.4% on placebo

Research designs investigating sustained melanocortin activity may prefer Melanotan 2's longer duration

Tirzepatide is $289/mo month-to-month, or from $249/mo on the 6-month plan and offers the same safety monitoring requirements as semaglutide, but individual patient responses and risk profiles differ between the two compounds

Maarbjerg and Jeanett Borregaard were employees of Novo Nordisk A/S at the time of conduct of the trial and preparation of this manuscript and are shareholders of Novo Nordisk A/S (current affiliation of SJM: Zealand Pharma A/S, Sborg, Denmark