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And some color changes signal genuine safety concerns while others are completely normal

GLP-1 medications mimic the natural action of the gut hormone glucagon-like peptide-1 (GLP-1), which regulates blood sugar levels and appetite

The most common include: Nausea Why it happens: Semaglutide works by slowing down how quickly the stomach empties food

Our primary comparison between Tirzepatide and Semaglutide yielded 25,060 matched pairs, while other treatment comparisons produced cohorts of varying sizes, from 7240 pairs for Tirzepatide versus Naltrexone/Bupropion to 18,892 pairs for Tirzepatide versus Phentermine (Fig