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The safety profile remained consistent across different dose levels, administration routes, and treatment durations

These models would better account for the genetic and molecular characteristics of breast cancer, enhancing prediction accuracy and providing more reliable support for research and clinical practice

Materials and Methods Animals The experimental treatments were carried out according to the guidelines for animal experiments of the Faculty of Disease Animal Model Research Center, Korea Research Institute of Bioscience and Biotechnology (Daejeon, Korea), as well as the Guidelines for the welfare and use of animals in cancer research

Peroxisome proliferator-activated receptor activators improve insulin sensitivity and reduce adiposity