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Kim et al., 2017)
Ample evidence suggests that lysosomes have been implicated in multiple RCD subroutines primarily through lysosomal membrane permeabilization (LMP) and subsequent release of cathepsins [84]
In addition, the oxidation of MT causes zinc release and is coupled to MTs expression to confer protection against OS
Notably, the acetylation of histones plays a role in the regulation of gene expression by facilitating transcription (i.e., mRNA synthesis), while deacetylated histones are usually associated with chromatin compaction and gene silencing
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