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3A and Supplementary Fig

Key points: On average, Wegovy supports weight loss of around 15% after one year, while orlistat supports around 8% Theoretically, combining the two medications could support more weight loss as they work differently in the body, but as no research has been conducted in this area we simply dont know what the impact would be 3) Key considerations if taking Wegovy with orlistat Wed recommend speaking with your doctor or prescribing pharmacist before taking Wegovy and orlistat together so they can continue to monitor your progress and vital blood markers

GLP-1 RAs offer improved glycaemia, weight loss and cardiovascular benefits in those for whom they are recommended by the guidelines, so it is important that we facilitate their initiation and continuation in as many appropriate people as possible

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