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[PMC free article: PMC7151476] [PubMed: 32283245] 43

IGF-1 DES promotes hyperplasia while healing peptides for injury recovery enhance tissue repair and reduce inflammation

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restricted to the outermost layers of skin , may be treated topically (Table 2) if the lesions location, the patients general health or the presence of co-morbidities mean excision is impractical or associated with an increased risk of complications or poor cosmetic outcome