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The phentermine versus semaglutide comparison and the phentermine versus GLP-1 analysis explain why incretin-based therapies have largely superseded older appetite suppressants in clinical practice

Herskovits, A

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The target genes of p53 involve the canonical ferroptosis pathway of GSH metabolism (e.g., SLC7A11), iron metabolism (TfR1 and SLC25A28), lipid metabolism, ROS generation, several oxidation/reduction related proteins, and the non-canonical ferroptosis pathway (66, 67)