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Hormone delivery method optimization Before starting a GLP-1 medication, evaluate your HRT delivery method: If you are on oral HRT: Talk to your provider about switching to transdermal delivery (patches or gels) for estrogen, and either a Mirena IUD or transvaginal delivery for progesterone

Mechanism ColonBroom's GLP-1 positioning is backed by real fiber science: fermentable fiber increases short-chain fatty acids, which activate receptors on gut L-cells that release GLP-1 and PYY, both of which increase fullness

PubMed , How Does Semaglutide Work? Mayo Clinic Diet , 23 May 2024, Kodoth, Varna, et al