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According to an analysis published last week in the Journal of the American Medical Association Health Forum, improved health outcomes notwithstanding, weight loss medications were not found to be cost-effective over a lifetime of projected use

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Hepatology 41(6):13131321 Juluri R, Vuppalanchi R, Olson J, nalp A, Van Natta ML, Cummings OW, Tonascia J, Chalasani N (2011) Generalizability of the nonalcoholic steatohepatitis Clinical Research Network histologic scoring system for nonalcoholic fatty liver disease

But the biological reality is far more nuanced than these percentages suggest