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Nature 472 (7341), 5763

DAPI-stained nuclei with blue fluorescence were viewed under laser confocal microscope (LSM 510

Antibodies targeting IL1- have also shown mixed, although more positive effects, particularly in reducing HbA1c with IL1- antagonism [206], with recent evidence suggesting that combined TNF-alpha and IL1- blockade may be most effective for glycemic control [207]