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Co-administration of single-dose furosemide with steady-state oral semaglutide resulted in a 28% increase in total furosemide exposure (AUC 0 ) and a 34% decrease in C max compared with patients not receiving oral semaglutide

Engaging in conversations about potential interactions will empower patients to reach educated conclusions regarding their medication regimen

The closest comparison is with AHK-Cu (Ala-His-Lys with copper), a related copper-binding tripeptide that shares the histidine-anchored coordination chemistry but has alanine rather than glycine at position 1

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