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Humans express a large family of genes that encode enzymes of the phosphoinositide phosphatase family, many of which are described in the following Table

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ROS have a dual role: on one hand, they serve as important signaling molecules in cellular signal transduction (43), while on the other hand, excessive ROS levels may oxidize mitochondrial DNA (mtDNA) (44, 45), membrane lipids, and mitochondrial proteins (46), leading to mitochondrial structural damage and potentially accelerating functional impairment (47, 48)

Las grasas de cadena corta o mediana (cido actico, cido propinico, cido valrico, cido butrico, etc) son capaces de atravesar la membrana de la mitocondria y llegar al interior de estas por s mismas