Although melanotic schwannomas have historically been considered as rather benign lesions, the 2021 WHO classification of central nervous system tumors defines MMNSTs as a potentially aggressive entity ( MMNSTs often harbor PRKAR1A mutations, particularly in patients with Carney complex ( Despite their classification as malignant, MMNSTs exhibit variable clinical behavior, ranging from indolent locally controlled disease to aggressive tumors with distant spread
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PLoS One 9, e89977 Gorboulev V, Schrmann A, Vallon V et al (2012) Na + -d-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion